Revista de Ingeniería

revinge | eISSN 2011-0049 | ISSN 0121-4993

Técnica de medición de fuerzas en células animales

No. 20 (2004-11-01)
  • Miller Hung Varela
    *Ing. Mecánico Universidad de los Andes, m-hung@uniandes.edu.co.
  • Alba Ávila
    **Profesor Asistente, Departamento de Ingeniería Eléctrica y Electrónica, Universidad de los Andes, a-avila@uniandes.edu.co.
  • Juan Carlos Briceño
    ***Profesor Asociado, Departamento de Ingeniería Mecánica, Universidad de los Andes, jbriceno@uniandes.edu.co.
https://doi.org/10.16924/revinge.20.4

Abstract

An experimental method was developed in order to join in vivo fibroblasts to an electronic device, a field effect transistor (ISFET), attempting to give a general view of the implications and requirements of animal cell culture and the different techniques required to handle the ISFET and its relation with biologic material. Signals from stimulated cells by mechanical means like hydrostatic pressure were registered establishing a value of voltage associated to the level of pressure applied. An hypothesis was established, related with the non linear behavior of the cells to mechanical induced stimulus and the possible improves and future applications of the method.

Keywords: fibroblastos, transistor de efecto de campo (ISFET), estímulos mecánicos a células